Sources :
1. Lohsiriwat V. Treatment of hemorrhoids: a coloproctologist's view.
DOI: 10.3748/wjg.v21.i31.9245
https://doi.org/10.3748/wjg.v21.i31.9245
2. Hengge UR et al. Adverse effects of topical glucocorticosteroids.
DOI: 10.1016/j.jaad.2005.01.010
https://doi.org/10.1016/j.jaad.2005.01.010
3. Aigner F et al. New insights into hemorrhoids.
DOI: 10.1038/s41572-023-00422-0
https://doi.org/10.1038/s41572-023-00422-0
4. Detralex Study Group. Diosmin, hesperidin, and related flavonoids in chronic venous disease.
PubMed: https://pubmed.ncbi.nlm.nih.gov/29443794/
5. Giannini I et al. Flavonoid mixture in the treatment of acute hemorrhoidal disease.
DOI: 10.1007/s10151-015-1302-9
https://doi.org/10.1007/s10151-015-1302-9
6. Serra R et al. Efficacy of low-dose diosmin therapy on symptoms and quality of life in chronic venous disease.
DOI: 10.3390/nu13030999
https://doi.org/10.3390/nu13030999
7. Sánchez M et al. Grape seed proanthocyanidins protect vascular endothelium from oxidative stress.
DOI: 10.1021/jf070372u
https://doi.org/10.1021/jf070372u
8. Li H et al. Anti-inflammatory and vascular-protective properties of hesperidin: a review.
DOI: 10.1016/j.jnutbio.2015.04.002
https://doi.org/10.1016/j.jnutbio.2015.04.002
9. Dubecq C et al. Hemodynamic effects of MPFF in chronic venous insufficiency.
PubMed: https://pubmed.ncbi.nlm.nih.gov/22027614/
10. Middleton E et al. Effects of plant flavonoids on inflammation and immunity.
PubMed: https://pubmed.ncbi.nlm.nih.gov/11121511/
11. Lete I, Allué J. Ruscus aculeatus extract in chronic venous disorders.
DOI: 10.1016/j.phymed.2006.08.006
https://doi.org/10.1016/j.phymed.2006.08.006
12. Belcaro G et al. OPC, Ruscus, and Hesperidin in venous insufficiency: dosage and effectiveness.
DOI: 10.1177/0003319710362042
https://doi.org/10.1177/0003319710362042
13. Ernst E. Hamamelis virginiana: a review of clinical trials.
DOI: 10.1007/s10354-004-0143-1
https://doi.org/10.1007/s10354-004-0143-1
14. Singh R et al. Topical hemorrhoid treatments: efficacy vs composition.
Example: https://ijpmsjournal.com/pdf/v12n4/13.pdf